反応 #55928

反応方程式

3,7-dimethyl-4-hydroxy-6-octen-1-ol

acetic anhydride

pyridine

→

8-acetoxy-2,6-dimethyl-5-hydroxy-2-octene

収率 45.0%

溶媒

ether

ether

反応条件

後処理

1. 1
   洗浄washed with saturated cupric sulfate solution (2×100 ml)
2. 2
   乾燥The organic phase is dried (Na2SO4)
3. 3
   その他evaporated in vacuo

実験手順

A mixture of 3,7-dimethyl-4-hydroxy-6-octen-1-ol (5.06 g, 29 mmole), acetic anhydride (3.06 g, 30 mmole), pyridine (4.75 g, 60 mmole) and ether (100 ml) is stirred at room temperature for 16 hours. The resulting mixture is treated with ether (200 ml) and washed with saturated cupric sulfate solution (2×100 ml). The organic phase is dried (Na2SO4) and evaporated in vacuo to give 8-acetoxy-2,6-dimethyl-5-hydroxy-2-octene as a colorless oil (2.27 g, 45%).

出典