反応 #558733

反応方程式

2-amino-5-(trifluoromethyl)benzonitrile

sulfamoyl chloride

→

N-(2-Cyano-4-trifluoromethylphenyl)sulfamide

反応条件

実験手順

Prepared as in Example 77a from 2-amino-5-(trifluoromethyl)benzonitrile (Example 86b) and sulfamoyl chloride. 1H NMR (400 MHz, DMSO-d6) δ 7.53 (s, 2H), 7.74-7.76 (d, J=8.4 Hz, 1H), 8.01-8.03 (dd, J=8.4 Hz, 1.6 Hz, 1H), 8.23-8.233 (d, J=1.2 Hz, 1H), 10.16 (b, 1H).

出典