反応 #55627

反応方程式

acetic acid

bis-(2,2,6,6-tetramethyl-4-piperidinyl) malonate

N-(3,5-di-tert.butyl-4-hydroxybenzyl)dimethylamine

lithium amide

→

3,5-di-tert.butyl-4-hydroxybenzyl-malonic acid-bis(2,2,6,6-tetramethyl-4-piperidinyl)ester

溶媒

toluene

反応条件

後処理

1. 1
   温度the mixture is refluxed for 3 hours
2. 2
   温度After cooling
3. 3
   洗浄the organic phase repeatedly washed with water
4. 4
   乾燥After drying over Na2SO4
5. 5
   濃縮the solution is concentrated in vacuo

実験手順

26 g (0.068 mole) of bis-(2,2,6,6-tetramethyl-4-piperidinyl) malonate and 17.8 g (0.068 mole) of N-(3,5-di-tert.butyl-4-hydroxybenzyl)dimethylamine are dissolved in 200 ml of toluene. After the addition of 0.5 g of lithium amide, the mixture is refluxed for 3 hours. After cooling, the mixture is neutralised with 1.5 ml of 1% acetic acid, and the organic phase repeatedly washed with water. After drying over Na2SO4, the solution is concentrated in vacuo to obtain, as oily residue, 3,5-di-tert.butyl-4-hydroxybenzyl-malonic acid-bis(2,2,6,6-tetramethyl-4-piperidinyl)ester.

出典