反応 #554599

反応方程式

boron boron tribromide

water

2-methoxytriphenylene

→

2-hydroxytriphenylene

収率 95.1%

溶媒

methylene chloride

methylene chloride

反応条件

後処理

1. 1
   温度while increasing temperature of the reaction solution to room temperature
2. 2
   ろ過followed by filtration
3. 3
   洗浄The resulting solid was washed with water and methanol

実験手順

Under an argon atmosphere, 13.9 g of 2-methoxytriphenylene was placed in a flask, and 300 mL of methylene chloride was added. The reaction solution was cooled to −78° C., and 54 mL of a solution of 1M boron boron tribromide in methylene chloride was dropwise added thereto. The reaction solution was stirred for 5 hours while increasing temperature of the reaction solution to room temperature. 100 mL of water was added to the reaction solution, followed by filtration. The resulting solid was washed with water and methanol to obtain 12.5 g (yield: 95%) of 2-hydroxytriphenylene.

出典