反応 #55449

反応方程式

3,4-Dimethoxyphenethylamine

N,N-diphenylglycine

→

N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(N,N-diphenylamino)acetamide

収率 66.9%

溶媒

ethylacetate

反応条件

後処理

1. 1
   温度After cooling
2. 2
   洗浄The resulting solution was washed with a 5% sodium bicarbonate aqueous solution and water
3. 3
   その他dried
4. 4
   workup.DISTILLATIONThe solvent was distilled off from the solution

実験手順

3,4-Dimethoxyphenethylamine (8.05 g) and N,N-diphenylglycine (10 g) were heated for 2 hours at 190° C. After cooling, the reaction mixture was dissolved in ethylacetate. The resulting solution was washed with a 5% sodium bicarbonate aqueous solution and water and then dried. The solvent was distilled off from the solution to give crystals of N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(N,N-diphenylamino)acetamide (11.5 g), mp 88° to 93° C.

出典