反応 #55307

反応方程式

2-(4-(diethylamino)benzoyl)-3,4,5,6-tetrachlorobenzoic acid

N,N,N',N'-tetraethyl-m-phenylenediamine

acetic anhydride

→

3-(2,4-bis(diethylamino)phenyl)-3-(4-(diethylamino)phenyl)-4,5,6,7-tetrachlorophthalide

収率 61.6%

溶媒

methanol

methanol

反応条件

実験手順

A mixture of 2-(4-(diethylamino)benzoyl)-3,4,5,6-tetrachlorobenzoic acid (8.70 g.), N,N,N',N'-tetraethyl-m-phenylenediamine (4.85 g.) and acetic anhydride (5 ml.) was heated (to 90° C.). Addition of methanol (10 ml.) and slurrying the resulting product with methanol (20 ml.) afforded 3-(2,4-bis(diethylamino)phenyl)-3-(4-(diethylamino)phenyl)-4,5,6,7-tetrachlorophthalide (I: X=Y4 =(CH3CH2)2N, Y2 =H, Z4 =Z5 =Z6 =Z7 =Cl) (7.85 g., m.p. 196°-197° C.).

出典