反応 #55303

反応方程式

2-(4-(dimethylamino)benzoyl)-3,4,5,6-tetrachlorobenzoic acid

N,N,N',N'-tetramethyl-m-phenylenediamine

acetic anhydride

→

3-(2,4-bis(dimethylamino)phenyl)-3-(4-(dimethylamino)phenyl)-4,5,6,7-tetrachlorophthalide

収率 73.6%

反応条件

後処理

1. 1
   温度cooled

実験手順

A mixture of 2-(4-(dimethylamino)benzoyl)-3,4,5,6-tetrachlorobenzoic acid (20.3 g.), N,N,N',N'-tetramethyl-m-phenylenediamine (88%, 9.3 g.) and acetic anhydride (74 ml.) was heated (to 95° C.) during one hour, then cooled, affording 3-(2,4-bis(dimethylamino)phenyl)-3-(4-(dimethylamino)phenyl)-4,5,6,7-tetrachlorophthalide (I: X=Y4 =(CH3)2N, Y2 =H, Z4 =Z5 =Z6 =Z7 =Cl) (20.3 g., m.p. 227°-229° C.).

出典