反応 #55253

反応方程式

2,2,6,6-tetramethyl-4-amino-piperidine

sodium carbonate

cyanuric chloride

→

white crystalline product

2-Chloro-4,6-bis-[(2,2,6,6-tetramethylpiperidin-4-yl)-amino]-1,3,5-triazine

溶媒

acetone

acetone

water

反応条件

後処理

1. 1
   その他prepared
2. 2
   その他is kept at 0°-5° C. by means of external cooling
3. 3
   workup.ADDITIONAfter the addition
4. 4
   ろ過Filtering
5. 5
   その他recrystallisation of the product from ethyl acetate/hexane

実験手順

62.4 g of 2,2,6,6-tetramethyl-4-amino-piperidine in 200 ml of acetone and, at the same time, 42.4 g of sodium carbonate dissolved in 100 ml of water are added to a finely dispersed suspension of cyanuric chloride, prepared by adding 36.9 g of the latter in 200 ml of boiling acetone to 400 ml of ice water. The temperature is kept at 0°-5° C. by means of external cooling. After the addition is complete, the reaction mixture is allowed slowly to warm to room temperature and is stirred at this temperature for 3 hours. Filtering and recrystallisation of the product from ethyl acetate/hexane gives 46.3 g of a white crystalline product, melting point 270° C.

出典