反応 #55169

反応方程式

3-chloro-1,2,4-triazole

1,3-diaminopropane

sodium ethoxide

→

3-(3-aminopropylamino)-1,2,4-triazole

溶媒

ethanol

反応条件

後処理

1. 1
   その他The solvent is removed

実験手順

A mixture of 3-chloro-1,2,4-triazole (10.3 g., 0.1 m.) and 1,3-diaminopropane (7.4 g., 0.1 m.) in ethanol containing sodium ethoxide is allowed to stand overnight. The solvent is removed to give 3-(3-aminopropylamino)-1,2,4-triazole. This intermediate is reacted with methyl isothiocyanate to give N-methyl-N'-[3-(3-(1,2,4-triazolyl)amino)propyl]thiourea.

出典