反応 #55154

反応方程式

Methyl 5-benzyl-4-oxazolecarboxylate

lithium aluminium hydride

→

5-benzyl-4-hydroxymethyloxazole

溶媒

tetrahydrofuran

反応条件

実験手順

Methyl 5-benzyl-4-oxazolecarboxylate is reduced with lithium aluminium hydride in tetrahydrofuran to give 5-benzyl-4-hydroxymethyloxazole, which on reaction with thionyl chloride is converted to 5-benzyl-4-chloromethyloxazole.

出典