反応 #55108

反応方程式

2-amino-4-hydroxymethylimidazole hydrochloride

picrate

hydrochloric acid

cysteamine hydrochloride

2-amino-4-[(2-aminoethyl)thiomethyl]imidazole

methyl isothiocyanate

→

N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea

反応条件

後処理

1. 1
   その他is obtained

実験手順

Reaction of 2-amino-4-hydroxymethylimidazole hydrochloride (which is obtained by treating the picrate salt with hydrochloric acid) with cysteamine hydrochloride and reaction of the resulting 2-amino-4-[(2-aminoethyl)thiomethyl]imidazole with methyl isothiocyanate by the methods of Example 1 gives N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea.

出典