反応 #55001

反応方程式

1,3-Diaminopropane

S-methyl-N-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiouronium sulphate

→

title compound

1,3-bis-[N'-(2-(5-Methyl-4-imidazolylmethylthio)ethyl)guanidino]propane

溶媒

water

反応条件

後処理

1. 1
   温度the mixture was heated
2. 2
   温度under reflux for 2 hours
3. 3
   濃縮concentration the residue
4. 4
   その他Recrystallisation from ethanol

実験手順

1,3-Diaminopropane (0.37 g) was added to a solution of S-methyl-N-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiouronium sulphate (2.93g) in water (10 ml) and the mixture was heated under reflux for 2 hours. Following concentration the residue was converted into the picrate with an aqueous solution of sodium picrate. Recrystallisation from ethanol afforded the title compound as the dipicrate (1.1 g) m.p. 114°-6°.

出典