反応 #54985

反応方程式

2-chloro-5-trifluoromethyl-aniline

ethoxymethylenemalononitrile

→

N-(2,2-dicyanovinyl)-2-chloro-5-trifluoromethylaniline

収率 70.0%

溶媒

ethanol

反応条件

後処理

1. 1
   温度the mixture is refluxed for 48 hours
2. 2
   温度After cooling
3. 3
   ろ過the precipitated product is collected by filtration
4. 4
   洗浄washed with ethanol
5. 5
   その他Recrystallisation from ethanol
6. 6
   その他affords the above product with a melting point of 166°-169° C.

実験手順

19.6 Parts of 2-chloro-5-trifluoromethyl-aniline and 12.2 parts of ethoxymethylenemalononitrile are dissolved in 125 parts of ethanol and the mixture is refluxed for 48 hours. After cooling, the precipitated product is collected by filtration and washed with ethanol. Recrystallisation from ethanol affords the above product with a melting point of 166°-169° C. and in a 70% yield.

出典