反応 #54974
ord-a79709e505384a2687bef6e5cd029a87
反応方程式
resorcinol
ethyl acetylacetate
ethanol
→
4-methyl-7-hydroxy-coumarin
収率 77.0%
反応条件
詳細条件
See reaction.notes.procedure_details.
実験手順
0.1 mole resorcinol and 0.1 mole ethyl acetylacetate in solution in 100 ml concentrated sulphuric acid are maintained at 5° C. for 3 hours. After recyrstallisation of the solid formed from ethanol, there are obtained 12.5 grams 4-methyl-7-hydroxy-coumarin, melting at 185° C.