反応 #548432

反応方程式

2-(5-carboxypentyl)-2-cyclopentenone

p-toluenesulfonic acid

→

2-(5-carbethoxypentyl)-2-cyclopentenone

溶媒

ethanol

反応条件

後処理

1. 1
   その他The solvent is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ether
3. 3
   洗浄The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution
4. 4
   乾燥dried (MgSO4)
5. 5
   その他evaporated
6. 6
   その他to give 1.371 g

実験手順

A solution of 1.309 g. (0.00668 mole) of 2-(5-carboxypentyl)-2-cyclopentenone (Example 52) and 90 mg. of p-toluenesulfonic acid in 150 ml. of ethanol is refluxed for 18 hours. The solvent is evaporated and the residue is dissolved in ether. The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution, dried (MgSO4), and evaporated to give 1.371 g. of a light yellow oil.

出典