反応 #54743

反応方程式

3-(2-dimethylaminoethoxy)-10-benzyl-9(10H)-acridinone

3-chloro-9(10H)-acridinone

benzyl bromide

sodium hydride

→

3-chloro-10-benzyl-9(10H)-acridinone

溶媒

dimethylformamide

反応条件

実験手順

3-(2-dimethylaminoethoxy)-10-benzyl-9(10H)-acridinone [IV; R' is C6H5CH2, R" is H, --O--Y--N=Z is 3--O--CH2CH2N(CH3)2 ], m.p. 134°-136° C. (light yellow powder). The intermediate 3-chloro-10-benzyl-9(10H)-acridinone, m.p. 186°-190° C. (yellow crystals) was prepared from 3-chloro-9(10H)-acridinone and benzyl bromide with sodium hydride in dimethylformamide.

出典