反応 #546520

反応方程式

(2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester

biphenyl-3-ol

(2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid

→

title compound

(2S)-3-{4-[2-(biphenyl-3-yloxy)-ethoxy]-phenyl}-2-methoxy-propionic acid

反応条件

後処理

1. 1
   その他(Example 285, Step 1), to produce a white solid

実験手順

The title compound was prepared from (2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (example 283, Step 2) and biphenyl-3-ol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid. (Example 285, Step 1), to produce a white solid. MS (ES) for C24H24O5 [M−H]−: 391.4.

出典