反応 #54520

反応方程式

3-trifluoromethoxy-benzaldehyde

nitro-ethane

n-butylamine

→

1-(3'-trifluoromethoxy-phenyl)-2-nitro-1-propene

収率 70.0%

反応条件

後処理

1. 1
   その他surmounted by a condenser
2. 2
   温度The mixture is heated for 20 hours at the reflux temperature

実験手順

32 g (0.17 mol) of 3-trifluoromethoxy-benzaldehyde, 32 ml of nitro-ethane and 2 ml of n-butylamine are introduced into a 100 ml flask surmounted by a condenser. The mixture is heated for 20 hours at the reflux temperature and then rectified. 29 g (70% yield) of 1-(3'-trifluoromethoxy-phenyl)-2-nitro-1-propene are collected as a yellow oil b.p. 90°-110° C./2mm. Hg.

出典