反応 #543549

反応方程式

NaBH4

9-cis-retinaldehyde

13-cis-retinol

→

9-cis-Retinol

反応条件

後処理

1. 1
   その他subsequently purified by normal phase HPLC essentially as we
2. 2
   その他have described for 11-cis-retinol synthesis and purification (25)

実験手順

All-trans-retinol was obtained as a gift from Dr. Christian Eckhoff of Hoffmann-LaRoche, Inc. (Nutley, N.J.), and 13-cis-retinol was purchased from Sigma. 9-cis-Retinol was synthesized by NaBH4 reduction of authentic 9-cis-retinaldehyde (Sigma) and subsequently purified by normal phase HPLC essentially as we have described for 11-cis-retinol synthesis and purification (25). All-trans-, 13-cis-, and 9-cis-retinaldehydes were purchased from Sigma.

出典