反応 #54149

反応方程式

2-(4-hydroxy-1-naphthoxy)propionic acid

potassium dihydrogen phosphate

potassium nitrosodisulfonate

→

4-(1-Carboxyethoxy)-1,2-naphthoquinone

溶媒

ethanol

water

反応条件

後処理

1. 1
   その他The yellow-brown solid was collected
2. 2
   洗浄washed with a litter water
3. 3
   その他dried (under nitrogen)

実験手順

To a solution of 38.0 g potassium dihydrogen phosphate in 7.5 l of distilled water (pH 4.0) was added 89.4 g (0.33 mol) potassium nitrosodisulfonate (Fremy's reagent). To this solution was added immediately a solution of 34.8 g (0.15 mol) of 2-(4-hydroxy-1-naphthoxy)propionic acid in 125 ml ethanol. The mixture was stirred for 2.5 hours under nitrogen at room temperature. The yellow-brown solid was collected, washed with a litter water and dried (under nitrogen). The yield was 30.0 g (81 percent). The crude product melted at 182° to 184° C.

出典