反応 #53941
ord-1f2a6879ce3540d882191229d4f4b02b
反応方程式
反応条件
詳細条件
See reaction.notes.procedure_details.
後処理
- 1その他the precipitated solid was isolated
実験手順
To 0.99 g (2.7 mmol) trans-[4-(4-Diethylcarbamoyl-butyl)-cyclohexyl]-methyl-carbamic acid tert-butyl ester in 5 ml dioxane were added 7 ml 4M HCl in dioxane at 0° C. The solution was stirred at RT for 2 h, diluted with ether, and the precipitated solid was isolated. 0.83 g (quant.) trans-5-(4-Methylamino-cyclohexyl)-pentanoic acid diethylamide.hydrochloride were isolated as white solid, mp. 122° C., MS: 269 (MH+).