反応 #53830

ord-652cc05d065f4b3785e7c8fccfe172f1

反応方程式

CN(C(=O)OC(C)(C)C)[C@H]1CC[C@H](O)CC1
trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester
BrCCCCBr
1,4-dibrombutane
→
CN(C(=O)OC(C)(C)C)[C@H]1CC[C@H](OCCCCBr)CC1
trans-[4-(4-Bromo-butoxy)-cyclohexyl]-methyl-carbamic acid tert-butyl ester

反応物

CN(C(=O)OC(C)(C)C)[C@H]1CC[C@H](O)CC1
trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester
BrCCCCBr
1,4-dibrombutane

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

In analogy to example 11.5, trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester and 1,4-dibrombutane were reacted to yield trans-[4-(4-Bromo-butoxy)-cyclohexyl]-methyl-carbamic acid tert-butyl ester as yellowish oil, MS: 364 (MH+, 1Br).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06858651B2uspto-grants-2005_02