反応 #53823

ord-90f5dd2790fa44009e0e5dbe767c8f70

反応方程式

CN(C(=O)Oc1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1
trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid 4-chloro-phenyl ester
BrCCCCBr
1,4-dibrombutane
→
CN(C(=O)Oc1ccc(Cl)cc1)[C@H]1CC[C@H](OCCCCBr)CC1
trans-[4-(4-Bromo-butoxy)-cyclohexyl]-methyl-carbamic acid 4-chloro-phenyl ester

反応物

CN(C(=O)Oc1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1
trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid 4-chloro-phenyl ester
BrCCCCBr
1,4-dibrombutane

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

In analogy to example 11.5, trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid 4-chloro-phenyl ester and 1,4-dibrombutane were reacted to yield trans-[4-(4-Bromo-butoxy)-cyclohexyl]-methyl-carbamic acid 4-chloro-phenyl ester as yellowish oil, MS:

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06858651B2uspto-grants-2005_02