反応 #53246

反応方程式

Tetrahydrothiophene

1-bromo-3,3-dimethyl-2-butanone

→

2-oxo-3,3-dimethylbutyltetrahydrothiophenium bromide

収率 80.4%

溶媒

acetonitrile

反応条件

後処理

1. 1
   その他a powder was precipitated
2. 2
   workup.ADDITIONAfter adding 100 ml of ethyl acetate to the reaction solution
3. 3
   ろ過the powder was filtered out
4. 4
   洗浄washed with ethyl acetate
5. 5
   その他dried

実験手順

Tetrahydrothiophene (11.8 g) was dissolved in 100 ml of acetonitrile, and 20 g of 1-bromo-3,3-dimethyl-2-butanone was slowly added to the above solution. The reaction solution was stirred at room temperature for two days, thereby a powder was precipitated. After adding 100 ml of ethyl acetate to the reaction solution, the powder was filtered out, washed with ethyl acetate and dried, thereby 24 g of 2-oxo-3,3-dimethylbutyltetrahydrothiophenium bromide was obtained.

出典