反応 #531846

反応方程式

9-phenylcarbazole

N-bromosuccinimide

toluene

→

3-bromo-9-phenyl-9H-carbazole

収率 99.0%

溶媒

ethyl acetate

反応条件

後処理

1. 1
   その他Into a 1000 mL three-neck flask were put
2. 2
   洗浄This suspending solution was washed with water, and magnesium sulfate
3. 3
   workup.ADDITIONwas added
4. 4
   その他so that moisture was removed
5. 5
   ろ過Then, the suspending solution was filtered
6. 6
   その他to provide a filtrate
7. 7
   その他was obtained
8. 8
   濃縮The obtained filtrate was concentrated
9. 9
   その他dried
10. 10
    その他the object of the synthesis
11. 11
    その他was obtained in a yield of 99% (synthesis scheme (a-6))

実験手順

Into a 1000 mL three-neck flask were put 24 g (100 mmol) of 9-phenylcarbazole, 18 g (100 mmol) of N-bromosuccinimide, 450 mL of toluene, and 200 mL of ethyl acetate, and the mixture was stirred for 45 hours at room temperature. This suspending solution was washed with water, and magnesium sulfate was added therein, so that moisture was removed. Then, the suspending solution was filtered to provide a filtrate was obtained. The obtained filtrate was concentrated and dried, whereby 32 g of a caramel-like solid of 3-bromo-9-phenyl-9H-carbazole, which was the object of the synthesis, was obtained in a yield of 99% (synthesis scheme (a-6)).

出典