反応 #53143

ord-59136c92f1894dfca344be0da35b67bc

反応方程式

Cl.NCc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1
(Z)-3-[1-(4-aminomethyl-phenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone-hydrochloride
CCC=O
propionaldehyde
[BH3-]C#N.[Na+]
sodium cyanoborohydride
→
CCCNCc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1
(Z)-3-[1-(4-propylaminomethyl-phenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone

反応物

Cl.NCc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1
(Z)-3-[1-(4-aminomethyl-phenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone-hydrochloride
CCC=O
propionaldehyde
[BH3-]C#N.[Na+]
sodium cyanoborohydride

試薬

なし

溶媒

CO
methanol

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Prepared analogously to Example 159 from (Z)-3-[1-(4-aminomethyl-phenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone-hydrochloride, propionaldehyde and sodium cyanoborohydride in methanol.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06855710B2uspto-grants-2005_02