反応 #529778

反応方程式

4,4'-Diphenol

triethylamine

Nonanoyl chloride

dimethylpyridine

→

titled compound

収率 159.7%

4-n-Nonanoyloxy-4'-hydroxybiphenyl

収率 159.7%

溶媒

dichloromethane

反応条件

後処理

1. 1
   抽出subjected to extraction with dichloromethane
2. 2
   乾燥The organic layer was dried over anhydrous magnesium sulfate
3. 3
   その他removed by evaporation
4. 4
   その他to give a crude product
5. 5
   その他It was purified by silica gel column chromatography (developer: hexane/ethyl acetate=3/2)

実験手順

4,4'-Diphenol (0.1 g) and triethylamine (0.57 g) were dissolved in dichloromethane (20 ml). Nonanoyl chloride (1.0 g) and dimethylpyridine (0.2 g) were added thereto, and the mixture was stirred at room temperature for about 20 hours. The reaction mixture was poured into ice-water and subjected to extraction with dichloromethane. The organic layer was dried over anhydrous magnesium sulfate and removed by evaporation to give a crude product. It was purified by silica gel column chromatography (developer: hexane/ethyl acetate=3/2) to give the titled compound (0.28 g).

出典