反応 #529776

反応方程式

hydrochloric acid

Nonanoyl chloride

dimethylaminopyridine

4'-Hydroxybiphenyl-4-carboxylic acid

→

titled compound

収率 86.3%

4'-n-nonanoyloxybiphenyl-4-carboxylic acid

収率 86.3%

溶媒

dichloromethane

triethylamine

反応条件

後処理

1. 1
   その他the organic layer was separated in a separating funnel
2. 2
   その他The solvent was removed by evaportaion
3. 3
   その他the residue was dried
4. 4
   洗浄after washing with n-hexane

実験手順

4'-Hydroxybiphenyl-4-carboxylic acid (3.5 g) and triethylamine (2.4 g) were dissolved in dichloromethane (30 ml). Nonanoyl chloride (4.3 g) and dimethylaminopyridine (0.2 g) were added to the solution, and the mixture was stirred at room temperature for about 20 hours. Dilute hydrochloric acid was added thereto, and the organic layer was separated in a separating funnel. The solvent was removed by evaportaion, and the residue was dried after washing with n-hexane to give the titled compound (5 g).

出典