反応 #52591

反応方程式

5-chlorosulfonyl-2-oxindole

morpholine

→

5-(morpholinosulfonyl)-2-oxindole

収率 74.9%

溶媒

dichloromethane

反応条件

後処理

1. 1
   ろ過The white precipitate was collected by vacuum filtration
2. 2
   洗浄washed with ethyl acetate and hexane
3. 3
   その他dried under vacuum at 40° C. overnight

実験手順

A suspension of 2.3 g of 5-chlorosulfonyl-2-oxindole and 2.2 g of morpholine in 50 mL of dichloromethane was stirred at room temperature for 3 hours. The white precipitate was collected by vacuum filtration, washed with ethyl acetate and hexane and dried under vacuum at 40° C. overnight to give 2.1 g (74% yield) of 5-(morpholinosulfonyl)-2-oxindole.

出典