反応 #5254

反応方程式

7-amino-cephalosporanic acid

boron trifluoride

allyl alcohol

→

3-allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid

溶媒

triethylamine

反応条件

後処理

1. 1
   その他were reacted
2. 2
   その他the 9 g of raw product was purified successively twice with hot hydrochloric acid and ammonium hydroxide

実験手順

Using the procedure of Step A of Example 8, 27.2 g of 7-amino-cephalosporanic acid, 170 ml of the etherate of boron trifluoride, 136 ml of allyl alcohol and 115 ml of triethylamine were reacted and the 9 g of raw product was purified successively twice with hot hydrochloric acid and ammonium hydroxide to obtain 4.72 g of 3-allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid.

出典