反応 #523489

反応方程式

potassium thiocyanate

hydrofluoric acid

α-methylnaphthalene

→

1-methyl-4-thionaphthamide

収率 97.0%

反応条件

後処理

1. 1
   workup.ADDITIONare added
2. 2
   workup.STIRRINGby stirring with ice
3. 3
   workup.DISTILLATIONby distilling off the greater part of the hydrofluoric acid in a steel apparatus
4. 4
   workup.STIRRINGbefore stirring with ice

実験手順

At a temperature and in the manner as described in Example 1, 39 g of potassium thiocyanate (0.4 mol) are stirred into 0.3 l of 98% hydrofluoric acid, 47 g of α-methylnaphthalene (0.33 mol) are added, and the mixture is stirred for 4 hours at room temperature. The reaction is then complete. Work-up is possible by stirring with ice, as described in the preceding Examples, or by distilling off the greater part of the hydrofluoric acid in a steel apparatus before stirring with ice. 64 g of 1-methyl-4-thionaphthamide having a melting point of 143° - 145° C are obtained, which corresponds to a yield of 97% of the theoretical yield, relative to α-methyl-naphthalene used.

出典