反応 #52168

ord-2c57fbc46f99407fad506d89d5f65f75

反応方程式

Oc1ccc2nc(-c3ccccc3)n(Cc3ccccc3)c2c1
1-Benzyl-6-hydroxy-2-phenylbenzimidazole
CC(C)OC(=O)CCCCCBr
6-bromo-hexanoic acid isopropyl ester
→
CC(C)OC(=O)CCCCCOc1ccc2nc(-c3ccccc3)n(Cc3ccccc3)c2c1
1-Benzyl-2-phenyl-6-[(5-(iso-propyl-oxycarbonyl)pentyl]oxy]-benzimidazole

反応物

Oc1ccc2nc(-c3ccccc3)n(Cc3ccccc3)c2c1
1-Benzyl-6-hydroxy-2-phenylbenzimidazole
CC(C)OC(=O)CCCCCBr
6-bromo-hexanoic acid isopropyl ester

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

1-Benzyl-6-hydroxy-2-phenylbenzimidazole is alkylated according to general operating instructions 2 with 6-bromo-hexanoic acid isopropyl ester. 1-Benzyl-2-phenyl-6-[(5-(iso-propyl-oxycarbonyl)pentyl]oxy]-benzimidazole is obtained as a resin.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06855714B2uspto-grants-2005_02