反応 #52043

反応方程式

4-chloro-3-nitro-quinoline

isobutyl amine

triethylamine

→

4-isobutyl-3-nitro quinoline

溶媒

toluene

反応条件

後処理

1. 1
   洗浄After washing
2. 2
   その他phase separation

実験手順

4-chloro-3-nitro-quinoline is reacted with isobutyl amine in the presence of triethylamine (TEA) at between −10 and +15° C. in toluene, while excluding moisture. After washing and phase separation, the organic solution is ready for the next step.

出典