反応 #51871

反応方程式

hydroxylamine

2-ureidoacetate

→

N-hydroxy-2-ureidoacetamide

溶媒

dioxane

反応条件

後処理

1. 1
   ろ過After 24 h the resin was filtered
2. 2
   洗浄washed with acetonitrile
3. 3
   その他purified by preparative reverse-phase (C18) HPLC

実験手順

The ArgoGel-Wang or ArgoGel-OH resin bound 2-ureidoacetate 6 (0.25 g) was treated with dioxane (1 mL) and aqueous 50% hydroxylamine (2 mL). After 24 h the resin was filtered, washed with acetonitrile and the filtrates combined and purified by preparative reverse-phase (C18) HPLC to yield product N-hydroxy-2-ureidoacetamide (I).

出典