反応 #51391

反応方程式

3,5-dichlorophenylacetic acid

L-alanine iso-butyl ester hydrochloride

→

title compound

N-[(3,5-diclorophenyl)acetyl]-L-alanine iso-butyl ester

反応条件

後処理

1. 1
   その他The reaction was monitored by tlc on silica gel (Rf=0.40 in 3% methanol/dichloromethane) and purification

実験手順

Following General Procedure BF above, and using 3,5-dichlorophenylacetic acid (from Example BC above) and L-alanine iso-butyl ester hydrochloride (from Example BB above), the title compound was prepared as a solid having a melting point of 115°-116° C. The reaction was monitored by tlc on silica gel (Rf=0.40 in 3% methanol/dichloromethane) and purification was by flash chromatography on silica gel using 3% methanol/dichloromethane as the eluant.

出典