反応 #51388

ord-df73a96a3c1b46e181f22eba45d4f13e

反応方程式

O=C(O)Cc1cccc([N+](=O)[O-])c1
3-nitrophenylacetic acid
CCOC(=O)[C@@H](N)CCSC.Cl
methionine ethyl ester hydrochloride
→
CCOC(=O)[C@H](CCSC)NC(=O)Cc1cccc([N+](=O)[O-])c1
title compound
CCOC(=O)[C@H](CCSC)NC(=O)Cc1cccc([N+](=O)[O-])c1
N-[(3-nitrophenyl)acetyl]methionine ethyl ester

反応物

O=C(O)Cc1cccc([N+](=O)[O-])c1
3-nitrophenylacetic acid
CCOC(=O)[C@@H](N)CCSC.Cl
methionine ethyl ester hydrochloride

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他The reaction was monitored by tlc on silica gel and purification
  2. 2
    その他was by recrystallization from butyl chloride

実験手順

Following General Procedure BG above and using 3-nitrophenylacetic acid (Aldrich) and methionine ethyl ester hydrochloride (Aldrich), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by recrystallization from butyl chloride.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06849650B2uspto-grants-2005_02