反応 #51324

反応方程式

3,4-dichloroaniline

2-ethylbutyl pyruvate

→

title compound

N-(3,4-dichlorophenyl)alanine 2-ethylbutyl ester

反応条件

後処理

1. 1
   その他The reaction was monitored by tlc on silica gel (Rf=0.6 in 25% EtOAc/hexanes) and purification

実験手順

Following General Procedure AA above and using 3,4-dichloroaniline (Aldrich) and 2-ethylbutyl pyruvate (prepared by following General Procedure AO above using 2-ethylbutanol (Aldrich) in place of iso-butanol), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.6 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).

出典