反応 #51230

反応方程式

N-(tert-butoxycarbonyl)piperazine

potassium carbonate

hydrochloric acid

butyl iodide

→

N-butylpiperazine.dihydrochloride

溶媒

dimethylformamide

反応条件

後処理

1. 1
   その他reaction

実験手順

To a dimethylformamide (7 ml) solution containing N-(tert-butoxycarbonyl)piperazine (1.0 g) were added potassium carbonate (742 mg) and then butyl iodide (1.09 g), and the mixture was stirred at room temperature for 15 hours to undergo reaction, thereby obtaining N-tert-butoxycarbonyl-N-butylpiperazine. This compound was acid-treated with hydrochloric acid to obtain N-butylpiperazine.dihydrochloride.

出典