反応 #51176

反応方程式

methyl 1-(3-(hydroxymethyl)phenyl)-5-oxopyrrolidine-3-carboxylate

pyridinium chlorochromate

→

desired product

methyl (3-formylphenyl)-5-oxopyrrolidine-3-carboxylate

溶媒

CH2Cl2

反応条件

後処理

1. 1
   ろ過The mixture was then filtered through a pad of celite
2. 2
   濃縮The filtrate was concentrated in vacuo

実験手順

To a solution of methyl 1-(3-(hydroxymethyl)phenyl)-5-oxopyrrolidine-3-carboxylate in CH2Cl2 was added pyridinium chlorochromate (PCC). The reaction was stirred at room temperature overnight. The mixture was then filtered through a pad of celite. The filtrate was concentrated in vacuo and the desired product was obtained after silica gel chromatograph. MS (ES+): 248.0 (M+H)+.

出典