反応 #5071

反応方程式

3-Ethenylbenzyl alcohol

carbon tetrachloride

triphenylphosphine

→

crude product

3-Ethenylbenzyl chloride

反応条件

後処理

1. 1
   温度The solution was refluxed overnight
2. 2
   workup.WAITleft
3. 3
   温度to cool
4. 4
   その他A white precipitate formed which
5. 5
   ろ過was filtered through celite
6. 6
   その他The filtrate was evaporated in vacuo

実験手順

3-Ethenylbenzyl alcohol (5.26 g) was dissolved in carbon tetrachloride (100 ml) and triphenylphosphine (10.2 g) added. The solution was refluxed overnight and then left to cool. A white precipitate formed which was filtered through celite. The filtrate was evaporated in vacuo to yield a crude product. The residue was purified by gravity chromatography on silica using 5% dichloromethane in petrol (60-80) as eluant. This yielded the pure product.

出典