反応 #50701

反応方程式

2-amino-5-methyl-benzoic acid

hydrogen

→

2-Carboxy-4-methylcyclohexan-1-yl-amine

溶媒

tetrahydrofuran

反応条件

後処理

1. 1
   温度After cooling
2. 2
   その他evaporation, 30 g o f 2-carboxy-4-methyl-cyclohexan-1-yl -amine
3. 3
   その他are obtained as a pale oil

実験手順

50 g (0.33 mol) of 2-amino-5-methyl-benzoic acid, dissolved in 100 ml of tetrahydrofuran, are hydrogenated for 14 hours at 200° C. and 200 bar hydrogen in the presence of 5 g of ruthenium/charcoal. After cooling and evaporation, 30 g o f 2-carboxy-4-methyl-cyclohexan-1-yl -amine are obtained as a pale oil.

出典