反応 #50652

反応方程式

2-methyl-1-undecene

parabromphenol

→

4-bromo-2-(1,1-dimethyldecyl)-phenol

反応条件

後処理

1. 1
   洗浄previously washed with water
2. 2
   洗浄rinsed with acetone and oven
3. 3
   その他dried for 3 hours at 80° C.
4. 4
   温度is heated at 100°-110° C. for 48 hours
5. 5
   その他chromatographed on a silica column (eluant
6. 6
   workup.ADDITIONa mixture of dichloromethane, 40% and hexane, 60%),

実験手順

A mixture of 2-methyl-1-undecene (35.6 g, 211 mmoles), parabromphenol (36.6 g, 211 mmoles) and Dowex 50×12 resin (100-200 mesh) previously washed with water, rinsed with acetone and oven dried for 3 hours at 80° C., is heated at 100°-110° C. for 48 hours. The mixture is then cooled to ambient temperature and chromatographed on a silica column (eluant: a mixture of dichloromethane, 40% and hexane, 60%), yielding 4-bromo-2-(1,1-dimethyldecyl)-phenol in the form of a pale yellow oil. (30.85 g, 43%).

出典