反応 #50636

ord-2120491cd3734273b49a4ac389fd8d89

反応方程式

CCOc1cc2ccc(=O)oc2cc1O
6-ethoxy-7-hydroxy-2H-1-benzopyran-2-one
OCCCCl
3-chloro-1-propanol
CC(C)O
isopropanol
→
CCOc1cc2ccc(=O)oc2cc1OCCCO
6-ethoxy-7-(3-hydroxypropoxy)-2H-1-benzopyran-2-one
収率 69.0%

反応物

CCOc1cc2ccc(=O)oc2cc1O
6-ethoxy-7-hydroxy-2H-1-benzopyran-2-one
OCCCCl
3-chloro-1-propanol
CC(C)O
isopropanol

試薬

なし

溶媒

COC(C)(C)C
TBME

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Method K; starting materials: 6-ethoxy-7-hydroxy-2H-1-benzopyran-2-one and 3-chloro-1-propanol; yield 69%; fusion point 96°-98° C. (from isopropanol and TBME).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05428038uspto-grants-1995_06