反応 #50613

反応方程式

Fumarate

6-(3-chloropropoxy)-7-methoxy-4-methyl-3-phenyl-2H-1-benzopyran-2-one

1-phenylpiperazine

isopropanol

→

7-methoxy-4-methyl-3-phenyl-6-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one

収率 66.0%

溶媒

acetone

反応条件

後処理

1. 1
   その他Method B (40 h at 50° C.)

実験手順

Method B (40 h at 50° C.); starting materials: 6-(3-chloropropoxy)-7-methoxy-4-methyl-3-phenyl-2H-1-benzopyran-2-one (example 79) and 1-phenylpiperazine; yield 66%; fusion point 168°-170° C. (from isopropanol). Fumarate: method E; yield 95%; fusion point 219°-221° C. (from acetone).

出典