反応 #50594

反応方程式

Fumarate

7-[3-(methanesulfonyloxy)propoxy]-6-(1-methylethoxy)-2H-1-benzopyran-2-one

4-phenylpiperidine

TBME

→

6-(1-methylethoxy)-7-[3-(4-phenyl-1-piperidinyl)propoxy]-2H-1-benzopyran-2-one

収率 69.0%

溶媒

acetone

ethanol

反応条件

後処理

1. 1
   その他Method B (24 h at 60° C.)

実験手順

Method B (24 h at 60° C.); starting materials: 7-[3-(methanesulfonyloxy)propoxy]-6-(1-methylethoxy)-2H-1-benzopyran-2-one (example 73) and 4-phenylpiperidine; yield 69%; fusion point 86°-87° C. (from TBME). Fumarate: method E; yield 90%; fusion point 164°-167° C. (from ethanol and acetone).

出典