反応 #50590

反応方程式

Fumarate

6-(3-chloropropoxy)-7-ethoxy-2H-1-benzopyran-2-one

1(2-methoxyphenyl)piperazine hydrochloride

isopropanol

→

7-ethoxy-6-{3-[4-(2-methoxyphenyl)-1-piperazinyl]propoxy}-2H-1-benzopyran-2-one

収率 49.0%

溶媒

ethanol

反応条件

後処理

1. 1
   その他Method A (48 h at 60° C.)

実験手順

Method A (48 h at 60° C.); starting materials: 6-(3-chloropropoxy)-7-ethoxy-2H-1-benzopyran-2-one (example 70) and 1(2-methoxyphenyl)piperazine hydrochloride; yield 49%; fusion point 78°-80° C. (from isopropanol). Fumarate: method E; yield 82%; fusion point 149°-150° C. (from ethanol).

出典