反応 #50587

反応方程式

Fumarate

6-(3-chloropropoxy)-7-ethoxy-2H-1-benzopyran-2-one

1-phenylpiperazine

methanol

→

7-ethoxy-6-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one

収率 57.0%

溶媒

ethanol

ethanol

反応条件

後処理

1. 1
   その他Method A (26 h at 60° C.)

実験手順

Method A (26 h at 60° C.); starting materials: 6-(3-chloropropoxy)-7-ethoxy-2H-1-benzopyran-2-one (see example 70) and 1-phenylpiperazine; yield 57%; fusion point 151° to 153° (from methanol and ethanol). Fumarate: method E; yield 78%; fusion point 170° to 173° C. (from ethanol).

出典