反応 #50585

反応方程式

6-[3-(methanesulfonyloxy)propoxy]-7-methoxy-2H-1-benzopyran-2-one

1-phenylpiperazine

Fumarate

→

7-methoxy-6-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one

収率 55.0%

溶媒

ethanol

ethanol

反応条件

後処理

1. 1
   その他Method A (23 h at 60° C.)

実験手順

Method A (23 h at 60° C.); starting materials: 6-[3-(methanesulfonyloxy)propoxy]-7-methoxy-2H-1-benzopyran-2-one (see example 67) and 1-phenylpiperazine; yield 55%; fusion point 124° to 125° C. (from ethanol). Fumarate: method E; yield 88%; fusion point 172° to 173° C. (from ethanol).

出典