反応 #502150

反応方程式

2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

morpholine

→

title compound

2-(3-Chlorobenzyl)-4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

反応条件

実験手順

In analogy to the preparation of Example 1, 150 mg (0.51 mmol) of 2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile are reacted with 448 mg (5.14 mmol) of morpholine to give 109 mg (63% of theory) of the title compound.

出典