反応 #502100

反応方程式

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylamine

ethyl 2-bromoacetate

→

compound

Ethyl[2-imino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-pyridin-1-yl]acetate hydrobromide

反応条件

後処理

1. 1
   ろ過A precipitate forms, and is recovered by filtration
2. 2
   洗浄washed with diethyl ether
3. 3
   乾燥with ethanol, and oven-dried under reduced pressure

実験手順

5.0 g of 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylamine in 7.6 ml of ethyl 2-bromoacetate are placed in a round-bottomed flask and the mixture is stirred at ambient temperature for 20 h. A precipitate forms, and is recovered by filtration, washed with diethyl ether and then with ethanol, and oven-dried under reduced pressure. 8.78 g of compound are obtained.

出典